Second Primary Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancers after Breast Cancer Diagnosis: Korea Central Cancer Registry
| العنوان: | Second Primary Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancers after Breast Cancer Diagnosis: Korea Central Cancer Registry |
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| المؤلفون: | So-Youn Jung, Jiwon Lim, Hyeong In Ha, Myong Cheol Lim, Young-Joo Won, Yoon Jung Chang, Eungyeong Lee |
| المصدر: | Cancer Research and Treatment : Official Journal of Korean Cancer Association |
| بيانات النشر: | Korean Cancer Association, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Oncology, Adult, Cancer Research, medicine.medical_specialty, Breast Neoplasms, Second primary neoplasms, Malignancy, Fallopian tube neoplasms, Breast cancer, Internal medicine, Republic of Korea, medicine, Humans, Registries, Risk factor, Peritoneal Neoplasms, Aged, Aged, 80 and over, Ovarian Neoplasms, Gynecologic Cancer, business.industry, Incidence (epidemiology), Cancer, Neoplasms, Second Primary, Epithelial ovarian cancer, Middle Aged, medicine.disease, Primary peritoneal, Cancer registry, Survival Rate, Serous fluid, Standardized mortality ratio, Original Article, Female, business |
| الوصف: | Purpose A prior history of breast cancer is a risk factor for the subsequent development of primary peritoneal, epithelial ovarian, and fallopian tubal (POFT) cancers. This study aimed to estimate the incidence of secondary POFT malignancy in breast cancer patients and the clinical outcomes of primary and secondary POFT cancer.Materials and Methods We searched the Korea Central Cancer Registry to find patients with primary and secondary POFT cancer who had breast cancer in 1999-2017. The incidence rate and standardized incidence ratio were calculated. Additionally, we compared the overall survival of patients with primary and secondary POFT cancer.Results Based on the age-standardized rate, the incidence of second primary POFT cancer after breast cancer was 0.0763 per 100,000 women, which increased in Korea between 1999 and 2017. Among the 30,366 POFT cancer patients, 25,721 were primary POFT cancer only, and 493 had secondary POFT cancer after a breast cancer diagnosis. Second primary POFT cancer patients were older at the time of diagnosis (55 vs. 53, p < 0.001) and had a larger proportion of serous histology (68.4% vs. 51.2%, p < 0.001) than patients with primary POFT. There were no differences between the two groups in tumor stage at diagnosis. The 5-year overall survival rates were 60.2% and 56.3% for primary and secondary POFT cancer, respectively (p=0.216).Conclusion The incidence of second primary POFT cancer after breast cancer increased in Korea between 1999 and 2017. Besides, second primary POFT cancer patients were diagnosed at older ages and had more serous histology. |
| اللغة: | English |
| تدمد: | 2005-9256 1598-2998 1999-2017 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14da57c6f641e768a64150c957856b56Test http://europepmc.org/articles/PMC8053875Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....14da57c6f641e768a64150c957856b56 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20059256 15982998 19992017 |
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