Fine‐needle aspiration cytology of Bacille Calmette‐Guerin adenitis: A perplexing distinct clinical entity
| العنوان: | Fine‐needle aspiration cytology of Bacille |
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| المؤلفون: | Nalini Gupta, Parikshaa Gupta, Manish Rohilla, Radhika Srinivasan, Arvind Rajwanshi, Pranab Dey, Aleena Jain, Shruti Gupta |
| المصدر: | Diagnostic Cytopathology. 49:226-231 |
| بيانات النشر: | Wiley, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Histology, Tuberculosis, Cytodiagnosis, Biopsy, Fine-Needle, Population, 030209 endocrinology & metabolism, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, Lymphadenitis, Cytology, Humans, Medicine, Lymphocytes, education, Histiocyte, Retrospective Studies, education.field_of_study, Granuloma, business.industry, Infant, General Medicine, Adenitis, medicine.disease, Dermatology, Giant cell, 030220 oncology & carcinogenesis, BCG Vaccine, Primary immunodeficiency, Female, Lymph Nodes, business, Complication |
| الوصف: | Background Bacille Calmette-Guerin (BCG) adenitis is a common complication of post-BCG vaccination. Awareness of this lesser known entity in fine-needle aspiration (FNA) is important to prevent misdiagnosis. Aim This study described the clinical presentation, cytomorphological features and disease pattern in patients with BCG adenitis. Materials and methods We analyzed a series of 15 patients with BCG adenitis seen from July 2017 to July 2019. The detailed clinical and cytomorphology of these cases were studied. Results Age of presentation ranged from 3 to 12 months. Male to female ratio was 2.75:1. A total of four children were diagnosed with primary immunodeficiency. Three children had acyanotic heart disease. Most of the children had left axillary lymph node enlargement. Cytomorphology showed the presence of polymorphs (66.7%), histiocytic aggregates (80%) and reactive lymphoid population (60%). Epithelioid granulomas (26.7%) and giant cells (6.7%) were present. The necrotic background was present in all but one case. Ziehl-Neelsen stain for acid-fast bacilli was positive in all but two cases. Conclusion A high index of clinical suspicion for BCG lymphadenitis should be kept in mind for patients who are recently vaccinated. FNA cytology, combined with clinical correlation, is useful for diagnosis and management. |
| تدمد: | 1097-0339 8755-1039 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103c144cc2ba7ad7c05f50b0e5b0cd81Test https://doi.org/10.1002/dc.24613Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....103c144cc2ba7ad7c05f50b0e5b0cd81 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10970339 87551039 |
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