Large penile plexiform neurofibroma in an 11-year old boy
| العنوان: | Large penile plexiform neurofibroma in an 11-year old boy |
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| المؤلفون: | Emmanuel Ezekiel Ayodeji, Fatungase Oluwabunmi Motunrayo, Salami Babatunde Abayomi, Ogundele Ibukunolu Olufemi, Amosu Lukmon Olusesan, Nwokoro Chingbundu Collins |
| المصدر: | Malawi Medical Journal; Vol 30, No 1 (2018); 49-51 Malawi Medical Journal |
| بيانات النشر: | Medical Association of Malawi, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Pathology, medicine.medical_specialty, Penile Diseases, Nerve root, Case Report, 03 medical and health sciences, 0302 clinical medicine, Plexiform neurofibroma, 030225 pediatrics, medicine, Humans, Neurofibroma, Neurofibromatosis, Child, Peripheral Nerve Sheath, Neurofibroma, Plexiform, business.industry, Glans penis, General Medicine, medicine.disease, Treatment Outcome, medicine.anatomical_structure, Sarcoma, business, 030217 neurology & neurosurgery, Penis |
| الوصف: | Background Neurofibromatosis is a genetically inherited disorder of the nervous system (brain and spinal cord) which mainly affects the development of nerve (neural) cell tissues, causing tumors (neurofibromas) to develop on nerves. It is the most common single gene disorder of the nervous system and inheritance is through autosomal dominance. They are usually classified into types 1 and 2, the type 1 is the commoner type and also known as superficial neurofibroma. Plexiform neurofibromas are the next most common type of tumor in individuals with type 1 neurofibroma. Plexiform neurofibromas are histologically benign tumors that are made up of a variety of cell types including neuronal axons, Schwann cells, fibroblasts, mast cells, macrophages, perineural cells and extracellular matrix materials such as collagen. They can occur in any part of the body and can grow throughout the person’s lifetime, often becoming disfiguring, disabling or deadly via compression of vital structures or conversion to a malignant sarcoma or malignant peripheral nerve sheath turmor. The aim of this report is to present a large penile plexiform neurofibroma which required extensive dissection for complete excision and reconstruction of the phallus and glans penis. Objectives To present a huge penile plexiform neurofibroma and the mode of surgical treatment. Methods The huge penile plexiform neurofibroma was completely excised and the penile defect resulting from the excision was repaired. Conclusion Plexiform neurofibromas are congenital tumors of peripheral nerve sheaths which may also develop near nerve roots deep within the body. They are usually benign but carry a malignant potential in 5-10% of patients. Plexiform neurofibromas are commoner in the face, chest and limbs but the index case occurred on the penile shaft. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1995-7262 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efcdee1b05d4ab21914506b11f3e89eTest https://www.ajol.info/index.php/mmj/article/view/168862Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0efcdee1b05d4ab21914506b11f3e89e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19957262 |
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