Detection of Specific Antibodies against Toscana Virus among Blood Donors in Northeastern Italy and Correlation with Sand Fly Abundance in 2014
| العنوان: | Detection of Specific Antibodies against Toscana Virus among Blood Donors in Northeastern Italy and Correlation with Sand Fly Abundance in 2014 |
|---|---|
| المؤلفون: | Alessandro Albieri, Mattia Calzolari, Rémi N. Charrel, Vanda Randi, Stefania Varani, Silvia Morini, Andrea Porcellini, Paolo Bonilauri, Nazli Ayhan, Romeo Bellini, Maria Carla Re, Nadia Pascarelli, Giada Rossini |
| المساهمون: | Morini S., Calzolari M., Rossini G., Pascarelli N., Porcellini A., Randi V., Re Maria Carla, Albieri A., Bonilauri P., Bellini R., Ayhan N., Charrel R., Varani S. |
| المصدر: | Microorganisms Microorganisms, Vol 8, Iss 2, p 145 (2020) Volume 8 Issue 2 |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Microbiology (medical), Veterinary medicine, 030231 tropical medicine, 030106 microbiology, viral meningitis, Biology, Toscana viru, Phlebotomus spp, Microbiology, Mediterranean Basin, Arbovirus, Article, 03 medical and health sciences, 0302 clinical medicine, Abundance (ecology), Virology, parasitic diseases, Viral meningitis, medicine, Seroprevalence, lcsh:QH301-705.5, Toscana virus, seroprevalence, fungi, neutralization, medicine.disease, biology.organism_classification, phlebotomus spp, Arboviru, Specific antibody, arbovirus, lcsh:Biology (General), Phlebovirus, sand fly, geographic locations |
| الوصف: | Toscana virus (TOSV) is a Phlebovirus transmitted by phlebotomine sand flies and is an important etiological agent of summer meningitis in the Mediterranean basin. Since TOSV infection is often asymptomatic, we evaluated the seroprevalence in blood donors (BDs) in the Bologna and Ferrara provinces (Northeastern Italy)&mdash the areas with the highest and lowest numbers of TOSV neuroinvasive cases in the region, respectively. A total of 1208 serum samples from BDs were collected in April&ndash June 2014 and evaluated for the presence of specific TOSV-IgG by ELISA. The IgG-reactive samples were confirmed by indirect immunofluorescence assay (IIF) and by microneutralization test (MN). Serum samples were defined as positive for anti-TOSV IgG when reactive by ELISA and by at least one second-level test TOSV seroprevalence was 6.8% in the Bologna province, while no circulation of TOSV was detected in the Ferrara province. Sand fly abundance in 2014 was also estimated by a geographic information system using a generalized linear model applied to a series of explanatory variables. TOSV seroprevalence rate was strongly associated with the sand fly abundance index in each municipality, pointing out the strong association between sand fly abundance and human exposure to TOSV. |
| وصف الملف: | ELETTRONICO; text/pdf; application/pdf |
| تدمد: | 2076-2607 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095c54c6f7f9abb89c6a274ebcddb6cbTest https://pubmed.ncbi.nlm.nih.gov/31973058Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....095c54c6f7f9abb89c6a274ebcddb6cb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20762607 |
|---|