Influence of age on the haemoglobin concentration of malaria-infected patients in a reference centre in the Brazilian Amazon
| العنوان: | Influence of age on the haemoglobin concentration of malaria-infected patients in a reference centre in the Brazilian Amazon |
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| المؤلفون: | Roberto C Reyes-Lecca, Márcia Aa Alexandre, Caterina Guinovart, Aline Alencar, Maria das Graças Costa Alecrim, Shelia Vítor-Silva, Mourão Maria Paula G, Wuelton Marcelo Monteiro, Marcus Vg Lacerda, André M. Siqueira, Janieldo A Cavalcante, Quique Bassat |
| المصدر: | Memórias do Instituto Oswaldo Cruz., Vol 109, Iss 5, Pp 569-576 (2014) Memórias do Instituto Oswaldo Cruz, Volume: 109, Issue: 5, Pages: 569-576, Published: 19 AUG 2014 Memórias do Instituto Oswaldo Cruz |
| بيانات النشر: | FapUNIFESP (SciELO), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, Microbiology (medical), medicine.medical_specialty, Pediatrics, lcsh:Arctic medicine. Tropical medicine, Adolescent, lcsh:RC955-962, Community control, Plasmodium falciparum, Plasmodium vivax, malaria, lcsh:QR1-502, Reproductive age, lcsh:Microbiology, Sex Factors, parasitic diseases, Malaria, Vivax, Prevalence, medicine, Humans, Major complication, Malaria, Falciparum, Child, Aged, Aged, 80 and over, anaemia, biology, business.industry, Amazon rainforest, Public health, Age Factors, Infant, Newborn, Infant, Anemia, Hemoglobin A, Articles, Middle Aged, biology.organism_classification, medicine.disease, haemoglobin, Case-Control Studies, Child, Preschool, Female, business, Brazil, Malaria |
| الوصف: | Anaemia is amongst the major complications of malaria, a major public health problem in the Amazon Region in Latin America. We examined the haemoglobin (Hb) concentrations of malaria-infected patients and compared it to that of malaria-negative febrile patients and afebrile controls. The haematological parameters of febrile patients who had a thick-blood-smear performed at an infectious diseases reference centre of the Brazilian Amazon between December 2009-January 2012 were retrieved together with clinical data. An afebrile community control group was composed from a survey performed in a malaria-endemic area. Hb concentrations and anaemia prevalence were analysed according to clinical-epidemiological status and demographic characteristics. In total, 7,831 observations were included. Patients with Plasmodium falciparum infection had lower mean Hb concentrations (10.5 g/dL) followed by P. vivax-infected individuals (12.4 g/dL), community controls (12.8 g/dL) and malaria-negative febrile patients (13.1 g/dL) (p < 0.001). Age, gender and clinical-epidemiological status were strong independent predictors for both outcomes. Amongst malaria-infected individuals, women in the reproductive age had considerably lower Hb concentrations. In this moderate transmission intensity setting, both vivax and falciparum malaria are associated with reduced Hb concentrations and risk of anaemia throughout a wide age range. |
| وصف الملف: | text/html |
| تدمد: | 1678-8060 0074-0276 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094882563e1f7c67b766fc87b5e6a954Test https://doi.org/10.1590/0074-0276140132Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....094882563e1f7c67b766fc87b5e6a954 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16788060 00740276 |
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