Mechanism Study on Chinese Medicine in Treatment of Nodular Goiter
| العنوان: | Mechanism Study on Chinese Medicine in Treatment of Nodular Goiter |
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| المؤلفون: | Chang-Lin, Wang, Ming-Zhou, Gao, Xiang-Ju, Gao, Xiang-Yu, Mu, Jie-Qiong, Wang, Dong-Mei, Gao, Ming-Qi, Qiao |
| المصدر: | Chinese Journal of Integrative Medicine. 29:566-576 |
| بيانات النشر: | Springer Science and Business Media LLC, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Complementary and alternative medicine, Pharmacology (medical), General Medicine |
| الوصف: | Nodular goiter has become increasingly prevalent in recent years. Clinically, there has been a burgeoning interest in nodular goiter due to the risk of progression to thyroid cancer. This review aims to provide a comprehensive summary of the mechanisms underlying the therapeutic effect of Chinese medicine (CM) in nodular goiter. Articles were systematically retrieved from databases, including PubMed, Web of Science and China National Knowledge Infrastructure. New evidence showed that CM exhibited multi-pathway and multi-target characteristics in the treatment of nodular goiter, involving hypothalamus-pituitary-thyroid axis, oxidative stress, blood rheology, cell proliferation, apoptosis, and autophagy, especially inhibition of cell proliferation and promotion of cell apoptosis, involving multiple signal pathways and a variety of cytokines. This review provides a scientific basis for the therapeutic use of CM against nodular goiter. Nonetheless, future studies are warranted to identify more regulatory genes and pathways to provide new approaches for the treatment of nodular goiter. |
| تدمد: | 1993-0402 1672-0415 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0803480289b0d51a60affa78f6fefa67Test https://doi.org/10.1007/s11655-022-3724-3Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....0803480289b0d51a60affa78f6fefa67 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19930402 16720415 |
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