The relationship between impaired control, impulsivity, and alcohol self-administration in nondependent drinkers
| العنوان: | The relationship between impaired control, impulsivity, and alcohol self-administration in nondependent drinkers |
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| المؤلفون: | Kristin M Corey, Courtney L. Vaughan, Vijay A. Ramchandani, Melanie L. Schwandt, Christian S. Hendershot, Bethany L. Stangl |
| المصدر: | Exp Clin Psychopharmacol |
| بيانات النشر: | American Psychological Association (APA), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, Alcohol Drinking, media_common.quotation_subject, Self Administration, Alcohol, Alcohol use disorder, Impulsivity, Article, Young Adult, chemistry.chemical_compound, Reward, Reward sensitivity, mental disorders, medicine, Humans, Pharmacology (medical), Young adult, media_common, Pharmacology, Ethanol, business.industry, Self-control, Middle Aged, medicine.disease, Alcoholism, Psychiatry and Mental health, Impaired control, chemistry, Impulsive Behavior, Administration, Intravenous, Female, Self Report, medicine.symptom, business, Self-administration, Clinical psychology |
| الوصف: | Impaired control over drinking is a significant marker of alcohol use disorder (AUD), and a potential target of intervention (Heather, Tebbutt, Mattick, & Zamir, 1993; Leeman, Toll, Taylor, & Volpicelli, 2009). Impaired control may be related to, but conceptually distinct from, impulsivity (Leeman, Patock-Peckham, & Potenza, 2012; Leeman, Ralevski, et al., 2014). However, the relationship between impaired control, impulsivity, and alcohol consumption, particularly in nondependent drinkers is less clear. This study aimed to characterize these relationships using a free-access intravenous alcohol self-administration (IV-ASA) paradigm in nondependent drinkers (N = 48). Results showed individuals with higher self-reported impaired control achieved higher blood alcohol concentrations (BAC) during the IV-ASA session and reported greater hedonic subjective responses to alcohol. Higher impaired control was also associated with greater positive urgency and reward sensitivity. Moderated-mediation analysis showed that the relationship between positive urgency and peak BAC was mediated by impaired control, and partially moderated by subjective alcohol response. These findings highlight the critical role of impaired control over drinking on alcohol consumption and subjective responses in nondependent drinkers. (PsycINFO Database Record (c) 2019 APA, all rights reserved). |
| تدمد: | 1936-2293 1064-1297 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0640f9ee8fbd2c9a0c62befd25b8a86cTest https://doi.org/10.1037/pha0000247Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0640f9ee8fbd2c9a0c62befd25b8a86c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19362293 10641297 |
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