An Intracerebral Hemorrhage Care Bundle Is Associated with Lower Case Fatality
| العنوان: | An Intracerebral Hemorrhage Care Bundle Is Associated with Lower Case Fatality |
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| المؤلفون: | Stephanie Lee, Mark Massyn, Camilla Sammut-Powell, Benjamin Bray, Emily Birleson, Richard Emsley, Adrian R Parry-Jones, Luca Cecchini, Joshua Rowland, Hiren C. Patel, Kyriaki Paroutoglou |
| المصدر: | Parry-Jones, A R, Sammut-Powell, C, Paroutoglou, K, Birleson, E, Rowland, J, Lee, S, Cecchini, L, Massyn, M, Emsley, R, Bray, B & Patel, H 2019, ' An intracerebral hemorrhage care bundle is associated with lower case-fatality ', Annals of Neurology, vol. 86, no. 4, pp. 495-503 . https://doi.org/10.1002/ana.25546Test |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, medicine.medical_specialty, Logistic regression, 03 medical and health sciences, 0302 clinical medicine, Case fatality rate, medicine, Humans, Registries, Stroke, Aged, Cerebral Hemorrhage, Aged, 80 and over, Intracerebral hemorrhage, business.industry, Disease Management, Odds ratio, Middle Aged, medicine.disease, Confidence interval, 030104 developmental biology, Blood pressure, Neurology, Emergency medicine, Female, Neurology (clinical), Neurosurgery, business, Patient Care Bundles, 030217 neurology & neurosurgery |
| الوصف: | OBJECTIVE: Anticoagulation reversal, intensive blood pressure lowering, neurosurgery and access to critical care might all be beneficial in acute intracerebral hemorrhage (ICH). We combined and implemented these as the 'ABC' hyperacute care bundle and sought to determine whether the implementation was associated with lower case fatality.METHODS: The ABC bundle was implemented from 1 June 2015 to 31 May 2016. Key process targets were set and a registry captured consecutive patients. We compared 30-day case fatality before, during and after bundle implementation with multivariable logistic regression and used mediation analysis to determine which care process measures mediated any association. Difference-in-difference analysis compared 30-day case fatality with 32,295 patients with ICH from 214 other hospitals in England and Wales using Sentinel Stroke National Audit Programme data.RESULTS: 973 ICH patients were admitted in the study period. Compared to before implementation, the adjusted odds of death by 30 days were lower in the implementation period (odds ratio [OR] 0·62; 95% confidence interval [CI] 0·38 to 0·97; p=0·03) and this was sustained after implementation (OR 0·40; 95%CI: 0·24 to 0·61; pINTERPRETATION: Implementation of the ABC care bundle was significantly associated with lower 30-day case fatality after ICH. This article is protected by copyright. All rights reserved. |
| وصف الملف: | application/pdf |
| تدمد: | 1531-8249 0364-5134 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063df508c4e7832b815d4c051876e6eeTest https://doi.org/10.1002/ana.25546Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....063df508c4e7832b815d4c051876e6ee |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15318249 03645134 |
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