Peptides Stimulate Expression of Signal Molecules in Neuronal Cultures from Animals of Different Age
| العنوان: | Peptides Stimulate Expression of Signal Molecules in Neuronal Cultures from Animals of Different Age |
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| المؤلفون: | V. Kh. Khavinson, R. S. Umnov, N. S. Linkova |
| المصدر: | Bulletin of Experimental Biology and Medicine. 157:701-704 |
| بيانات النشر: | Springer Science and Business Media LLC, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Nervous system, chemistry.chemical_classification, Aging, biology, Brain cortex, Vimentin, Peptide, General Medicine, Neuroprotection, General Biochemistry, Genetics and Molecular Biology, Rats, Cell biology, medicine.anatomical_structure, chemistry, Cell culture, medicine, biology.protein, Animals, Serotonin, Rats, Wistar, Peptides |
| الوصف: | Molecular mechanisms of the neuroprotective effect of peptide T-33 and cortexin were studied on organotypic cultures of the brain from young and old Wistar rats. The effective concentration of peptide T-33 stimulating proliferative activity of neurons considerably surpassed that of cortexin. Cortexin and peptide T-33 stimulated the expression of serotonin, Ki-67, and vimentin in cells of the brain cortex; peptide T-33 was most effective in this respect. |
| تدمد: | 1573-8221 0007-4888 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0178e32250af3ef765a8e081e5157794Test https://doi.org/10.1007/s10517-014-2646-2Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....0178e32250af3ef765a8e081e5157794 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15738221 00074888 |
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