Passiflora edulis (var. Flavicarpa) Juice Supplementation Mitigates Isoproterenol‐induced Myocardial Infarction in Rats
| العنوان: | Passiflora edulis (var. Flavicarpa) Juice Supplementation Mitigates Isoproterenol‐induced Myocardial Infarction in Rats |
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| المؤلفون: | Annie Abraham, R.S. Soumya, K Binu Raj |
| المصدر: | Plant Foods for Human Nutrition. 76:189-195 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Antioxidant, medicine.medical_treatment, chemistry.chemical_element, Calcium, 03 medical and health sciences, chemistry.chemical_compound, 0404 agricultural biotechnology, Internal medicine, Lactate dehydrogenase, medicine, Myocardial infarction, Metoprolol, Cardioprotection, 030109 nutrition & dietetics, biology, Triglyceride, 04 agricultural and veterinary sciences, medicine.disease, 040401 food science, Endocrinology, chemistry, Chemistry (miscellaneous), biology.protein, Creatine kinase, Food Science, medicine.drug |
| الوصف: | The common reason for mortality globally is myocardial infarction. The study aimed to evaluate Passiflora edulis (PE) fruit juice potential in the experimental isoproterenol (ISO) treated rat model to manage myocardial injury. ISO (20 mg/100 g body weight) treated rats showed a significant increment in serum marker enzymes lactate dehydrogenase (LDH) and creatinine kinase (CK), serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), serum alkaline phosphatase (ALP) and serum acid phosphatase (ACP) activity. Besides, phosphorus and calcium, serum cholesterol, and triglyceride levels (TG) were high in ISO groups. A significant decline in antioxidant activity and histopathological alteration was observed in ISO treated groups. PE juice pre-treatment (2 ml/kg) for 28 days and ISO treatment on the 29th and 30th days showed a protective effect on distorted biochemical and histopathologic parameters compared with reference drug metoprolol. These findings indicate the cardioprotective effect of PE juice on ISO-induced myocardial infracted rats. |
| تدمد: | 1573-9104 0921-9668 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::f22d5c9f6a34b095c2b4219b6adb0e5fTest https://doi.org/10.1007/s11130-021-00891-xTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........f22d5c9f6a34b095c2b4219b6adb0e5f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15739104 09219668 |
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