Function regulation of hemoproteins through their specific interaction with unnatural organic molecules or molecular assemblies
العنوان: | Function regulation of hemoproteins through their specific interaction with unnatural organic molecules or molecular assemblies |
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المؤلفون: | Itaru Hamachi |
المصدر: | Seibutsu Butsuri. 36:181-185 |
بيانات النشر: | Biophysical Society of Japan, 1996. |
سنة النشر: | 1996 |
مصطلحات موضوعية: | chemistry.chemical_compound, Hemeprotein, Membrane, Protein molecules, chemistry, Stereochemistry, Biophysics, Molecule, Phenylboronic acid, Lipid bilayer, Function (biology), Organic molecules |
الوصف: | Site specific incorporation of unnatural molecules into native proteins are proven to be one of the most promising methodologies in protein molecules engineering. In this article, I describe successful examples of function regulation of hemoproteins by interactions with phenylboronic acid as a sugar recognition site and maleic acids as controlling sites of electrostatic repulsion. As another approach, molecular assemblies such as lipid bilayer membranes, are demonstrated to be potential one which enable the functional conversion of the bound-protein through noncovalent but domain-specific perturbations. |
تدمد: | 1347-4219 0582-4052 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::e6bffae4637dc602d5c8aaee7b9bc9e2Test https://doi.org/10.2142/biophys.36.181Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi...........e6bffae4637dc602d5c8aaee7b9bc9e2 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 13474219 05824052 |
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