Characterization and Molecular Design of Hemoproteins by Protein Engineering
| العنوان: | Characterization and Molecular Design of Hemoproteins by Protein Engineering |
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| المؤلفون: | Isao Morishima, Koichiro Ishimori |
| المصدر: | Seibutsu Butsuri. 33:212-218 |
| بيانات النشر: | Biophysical Society of Japan, 1993. |
| سنة النشر: | 1993 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Hemeprotein, Cytochrome, biology, Cytochrome b, Oxygen transport, Protein engineering, Amino acid, chemistry.chemical_compound, Myoglobin, chemistry, Biochemistry, biology.protein, Oxygen binding |
| الوصف: | Hemoproteins are a class of biologically important proteins which have three distinct functions: reversible oxygen transport (myoglobin and hemoglobin), reversible electron transfer (cytochrome b's and c's), and catalytic activity (cytochrome P-450's and peroxidases). Recent protein engineering techniques have played important roles in understanding the regulation mechanism of the various functions in hemoproteins. In this review, we discuss the regulation mechanism of enzymatic oxidation reactions, modular structure, and cooperative oxygen binding in hemoproteins by using amino acid substituted proteins. |
| تدمد: | 1347-4219 0582-4052 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::d5e21e7018e6f9d84cefeba023465463Test https://doi.org/10.2142/biophys.33.212Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........d5e21e7018e6f9d84cefeba023465463 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13474219 05824052 |
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