Serum Serotonin as a Biomarker of the Efficacy of PAP-Therapy in Sleep Apnea Syndrome
| العنوان: | Serum Serotonin as a Biomarker of the Efficacy of PAP-Therapy in Sleep Apnea Syndrome |
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| المؤلفون: | Irina Madaeva, L. V. Natyaganova, Lyubov Kolesnikova, O. N. Berdina, E B Ukhinov, T. A. Bairova, A. V. Bel'skikh, Natalya Semenova, Sergey I. Kolesnikov, N. A. Kurashova |
| المصدر: | Bulletin of Experimental Biology and Medicine. 171:713-715 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Sleep apnea, Intermittent hypoxia, General Medicine, Hypoxia (medical), medicine.disease, Sleep in non-human animals, Gastroenterology, General Biochemistry, Genetics and Molecular Biology, Obstructive sleep apnea, Potential biomarkers, Internal medicine, Medicine, Biomarker (medicine), Serotonin, medicine.symptom, business |
| الوصف: | Serum serotonin levels were determined by HPLC in 30 patients with diagnosed obstructive sleep apnea syndrome before and after 3-month course of PAP-therapy and in 14 subjects without obstructive sleep apnea symptoms. It was found that elimination of hypoxic conditions was associated with an increase in serotonin level. The results demonstrate the effectiveness of PAP-therapy during sleep and allow assessing the role of serotonin as a potential biomarker of intermittent hypoxia during sleep. |
| تدمد: | 1573-8221 0007-4888 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::c76119253aae27a3efccdb087a7899beTest https://doi.org/10.1007/s10517-021-05301-5Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........c76119253aae27a3efccdb087a7899be |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15738221 00074888 |
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