Practical Large-Scale Preparation of (±)-2-exo-Norbornyl Carboxylic Acid and Its Improved Isolation As the Sodium Salt
| العنوان: | Practical Large-Scale Preparation of (±)-2-exo-Norbornyl Carboxylic Acid and Its Improved Isolation As the Sodium Salt |
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| المؤلفون: | Thomas Storz, Charles C. Wu, Jianxin Gu, Frederick Vyverberg, Karen Sutherland, Varsolona Richard J |
| المصدر: | Organic Process Research & Development. 15:942-945 |
| بيانات النشر: | American Chemical Society (ACS), 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | chemistry.chemical_classification, chemistry, Carboxylic acid, Organic Chemistry, Organic chemistry, Physical and Theoretical Chemistry, 2-Norbornyl cation, humanities, Hydroformylation, Sodium salt |
| الوصف: | A practical, robust, and high-yielding three-step−one-pot procedure for the diastereoselective synthesis of (±)-2-exo-norbornyl carboxylic acid starting from norbornylene has been found and demonstrated on multikilogram scale, setting a new benchmark for low-pressure hydroformylation of cyclic, bridged olefins. The newly found, nonhygroscopic crystalline sodium salt of this acid provides a practical isolation point. |
| تدمد: | 1520-586X 1083-6160 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::a98fa14092208b750f0a63b27782bd14Test https://doi.org/10.1021/op100284aTest |
| رقم الانضمام: | edsair.doi...........a98fa14092208b750f0a63b27782bd14 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1520586X 10836160 |
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