Normal Pressure Hydrocephalus in Down Syndrome: The Report of Two Cases
| العنوان: | Normal Pressure Hydrocephalus in Down Syndrome: The Report of Two Cases |
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| المؤلفون: | Massimo Marano, Angelo Pompucci, Mariagrazia Rossi, Alfonso Fasano, Gianpaolo Petrella, Ernesto Coletta, Francesco Motolese, Vincenzo Di Lazzaro |
| المصدر: | Journal of Alzheimer's Disease. 77:979-984 |
| بيانات النشر: | IOS Press, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Senescence, Down syndrome, Pediatrics, medicine.medical_specialty, Adult patients, business.industry, General Neuroscience, 05 social sciences, General Medicine, Disease, medicine.disease, Shunt (medical), 03 medical and health sciences, Psychiatry and Mental health, Clinical Psychology, 0302 clinical medicine, Cerebrospinal fluid, Normal pressure hydrocephalus, 0502 economics and business, Intellectual disability, medicine, 050211 marketing, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery |
| الوصف: | Down syndrome (DS) is the most common cause of intellectual disability in infants and has a well-known relationship with the Alzheimer’s disease. The association between DS and the other pathologies of senescence, such as normal pressure hydrocephalus (NPH), has been poorly investigated. This series included two DS patients with NPH. In both cases, NPH symptoms were initially misdiagnosed as DS associated senescence. Patients were treated with ventricular-peritoneal shunt, showing a sustained improvement (1 and 4 years of follow-up). To our knowledge, this is the first description of the occurrence of NPH in adult patients with DS and surgical outcomes. |
| تدمد: | 1875-8908 1387-2877 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::9ee8a92c913dcc532396246f5d19d799Test https://doi.org/10.3233/jad-200409Test |
| رقم الانضمام: | edsair.doi...........9ee8a92c913dcc532396246f5d19d799 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18758908 13872877 |
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