Molecular Cloning and Expression Analysis of the Complementary Deoxyribonucleic Acid for Chicken Inhibin/Activin βB Subunit1
| العنوان: | Molecular Cloning and Expression Analysis of the Complementary Deoxyribonucleic Acid for Chicken Inhibin/Activin βB Subunit1 |
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| المؤلفون: | Patricia A. Johnson, A. J. Davis, Danielle J. Hecht, Carrie F. Brooks |
| المصدر: | Biology of Reproduction. 62:1128-1134 |
| بيانات النشر: | Oxford University Press (OUP), 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | chemistry.chemical_classification, endocrine system, Protein subunit, Peptide, Cell Biology, General Medicine, Biology, Peptide hormone, Molecular cloning, Molecular biology, Amino acid, Reproductive Medicine, chemistry, Complementary DNA, Coding region, Peptide sequence |
| الوصف: | Inhibins and activins are dimeric peptide hormones that play an integral role in the intraovarian regulation of folliculogenesis. The domestic hen, with its well-defined follicular hierarchy, provides a unique model in which to study the role of these hormones in follicular development. In the present study, the complete coding sequence and deduced amino acid sequence for the chicken inhibin/activin βB subunit has been determined from cDNA clones isolated from a chicken ovarian granulosa cell library. This βB-subunit cDNA predicts a precursor protein of 392 amino acids containing the mature C-terminal 115 amino acid βB subunit. When compared to the βB subunit isolated from a variety of species, the chicken cDNA clone showed high nucleotide identity in the full-length coding region (>70%) and in the mature coding region (>80%). In addition, the deduced amino acid sequence of chicken βB subunit showed greater than 95% identity compared to other species in the mature peptide region. Expression of th... |
| تدمد: | 1529-7268 0006-3363 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::9d15d1e94a3913c3925d056c92c2eb07Test https://doi.org/10.1095/biolreprod62.5.1128Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........9d15d1e94a3913c3925d056c92c2eb07 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15297268 00063363 |
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