Cardiac resynchronization therapy (CRT) device replacement considerations: upgrade or downgrade? A complex decision in the current clinical setting
| العنوان: | Cardiac resynchronization therapy (CRT) device replacement considerations: upgrade or downgrade? A complex decision in the current clinical setting |
|---|---|
| المؤلفون: | Eleni S. Nakou, Konstantinos S. Nakos, Eleftherios M. Kallergis, Emmanuel N. Simantirakis, Panos E. Vardas |
| المصدر: | EP Europace. 19:705-711 |
| بيانات النشر: | Oxford University Press (OUP), 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, genetic structures, Cost effectiveness, medicine.medical_treatment, Cardiac resynchronization therapy, 030204 cardiovascular system & hematology, Downgrade, 03 medical and health sciences, 0302 clinical medicine, health services administration, Physiology (medical), medicine, cardiovascular diseases, 030212 general & internal medicine, Intensive care medicine, business.industry, Cardiac Resynchronization Therapy Devices, Equipment Failure Analysis, Evidence-based medicine, medicine.disease, Clinical trial, Heart failure, cardiovascular system, Physical therapy, Cardiology and Cardiovascular Medicine, business, circulatory and respiratory physiology |
| الوصف: | There are limited data about the management of patients presenting for elective generator replacements in the setting of previously implanted cardiac resynchronization therapy (CRT) devices that are nearing end-of-life. The individual patient's clinical status and concomitant morbidities may evolve so that considerations may include not only replacement of the pulse generator, but also potentially changing the type of device [e.g. downgrading CRT-defibrillator (CRT-D) to CRT-pacemaker (CRT-P) or ICD or upgrading of CRT-P to CRT-D]. Moreover, the clinical evidence for CRT-D/CRT-P implantation may change over time, with ongoing research and availability of new trial data. In this review we discuss the ethical, clinical and financial implications related to CRT generator replacements and the need for additional clinical trials to better understand which patients should undergo CRT device downgrading or upgrading at the time of battery depletion. |
| تدمد: | 1532-2092 1099-5129 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::865dfb2f2507d84022d0720f81e1dc62Test https://doi.org/10.1093/europace/euw317Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........865dfb2f2507d84022d0720f81e1dc62 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15322092 10995129 |
|---|