In this talk, we will first review the state of the art in wireless capsule endoscopy and the challenges in the development of active capsule endoscopes and the associated automatic diagnosis system based on images obtained by the wireless capsule endoscopes. Our recent work on the development of wireless capsule endoscope dynamic model, accurate 3D localization of the wireless capsule endoscope, and actuation mechanisms will then be presented, together with analytical, simulation and experimental results we have obtained. We will finish the talk with a brief summary of the contents presented and our views on future possibilities and research opportunities in the concerned research areas.
