Placental transfusion in preterm neonates of 30–33 weeks’ gestation: a randomized controlled trial
| العنوان: | Placental transfusion in preterm neonates of 30–33 weeks’ gestation: a randomized controlled trial |
|---|---|
| المؤلفون: | William Tarnow-Mordi, Bikramjit Das, Lakhbir Kaur Dhaliwal, Venkataseshan Sundaram, Praveen Kumar, Alpana Ghadge |
| المصدر: | Journal of Perinatology. 38:496-504 |
| بيانات النشر: | Springer Science and Business Media LLC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Pregnancy, medicine.medical_specialty, Cord, business.industry, Obstetrics, Incidence (epidemiology), Obstetrics and Gynecology, Gestational age, medicine.disease, Umbilical cord, law.invention, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Randomized controlled trial, law, 030225 pediatrics, Pediatrics, Perinatology and Child Health, Necrotizing enterocolitis, medicine, Gestation, 030212 general & internal medicine, business |
| الوصف: | To compare effect of placental transfusion by delayed cord clamping (DCC) or cord milking (CM) with early cord clamping (ECC) on a composite of mortality or abnormal neurological status at 40 weeks’ post-menstrual age (PMA) and 24–30 months’ chronological age in neonates of 30–33 weeks’ gestation. Randomized, controlled trial. A composite of mortality or abnormal neurological status at 40 weeks PMA and survival free of neurodevelopmental abnormalities at 24–30 months’ chronological age. A total of 461 neonates were randomized to placental transfusion (n = 233) or to ECC (n = 228). Among those assigned to placental transfusion group, 173 underwent DCC while in the remaining 60, CM was done. Incidence of mortality or abnormal neurological status at 40 weeks PMA (43 (18%) vs 35 (15%), RR (95% CI) 1.2 (0.8, 1.8), p = 0.4) and survival free of neurodevelopmental impairment at 24–30 months of chronological age (99 (47%) vs. 100 (50%); RR (95% CI): 0.9 (0.8, 1.2); P = 0.9) was similar between the study groups. The placental transfusion group showed a trend towards lower incidence of necrotizing enterocolitis. In 30–33 weeks’ gestation preterm neonates, placental transfusion as compared to early cord clamping resulted in similar mortality or abnormal neurological status at 40 weeks PMA and at 24–30 months of chronological age. |
| تدمد: | 1476-5543 0743-8346 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::3b3d29d5875eeb6c65caef0345102f8fTest https://doi.org/10.1038/s41372-018-0064-4Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........3b3d29d5875eeb6c65caef0345102f8f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765543 07438346 |
|---|