The Effect of Prior Continuous Glucose Monitoring Use on Glycemic Outcomes in the Pivotal Trial of the MiniMed™ 670G Hybrid Closed-Loop System
| العنوان: | The Effect of Prior Continuous Glucose Monitoring Use on Glycemic Outcomes in the Pivotal Trial of the MiniMed™ 670G Hybrid Closed-Loop System |
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| المؤلفون: | Timothy S. Bailey, Scott W. Lee, Toni L. Cordero, John H. Shin, Satish K. Garg, Ronald L. Brazg, Francine R. Kaufman |
| المصدر: | Diabetes Technology & Therapeutics. 19:749-752 |
| بيانات النشر: | Mary Ann Liebert Inc, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, endocrine system diseases, Diabetic ketoacidosis, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Hypoglycemia, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Diabetes mellitus, Internal medicine, medicine, 030212 general & internal medicine, Glycemic, Type 1 diabetes, Continuous glucose monitoring, business.industry, nutritional and metabolic diseases, medicine.disease, Medical Laboratory Technology, chemistry, Glycated hemoglobin, business, Closed loop |
| الوصف: | A 3-month pivotal trial using the MiniMed™ 670G hybrid closed-loop (HCL) system in adolescent and adult patients with type 1 diabetes (T1D), relative to a 2-week baseline run-in period, resulted in increased sensor glucose (SG) values in target range (71–180 mg/dL), reduced HbA1c levels, and no events of diabetic ketoacidosis or severe hypoglycemia (Clinicaltrials.gov: NCT02463097). This brief report evaluated how prior continuous glucose monitoring (CGM) experience influenced glycemic outcomes, in the same pivotal trial. HbA1c levels and the percentage of SG values in low, high, and in-target ranges were analyzed from participants (n = 124) completing the Hybrid Closed-Loop Pivotal Trial in T1D. There were 78 individuals comprising the prior CGM group and 46 comprising the no prior CGM group. Compared to baseline, HbA1c was reduced from 7.4% ± 0.9% to 6.9% ± 0.7% for the prior CGM group and from 7.5% ± 0.9% to 6.8% ± 0.5% for the no prior CGM group. For those with prior CGM experience, the mean ... |
| تدمد: | 1557-8593 1520-9156 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::15cef7cf088a6cd70aabf4bf255b51afTest https://doi.org/10.1089/dia.2017.0208Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........15cef7cf088a6cd70aabf4bf255b51af |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15578593 15209156 |
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