76-LB: Differences in Time-In-Range, Glycemic Variability, and the Glucose Management Indicator in Pregnant Women with Type 1 (T1D), Type 2 (T2D), and Gestational Diabetes (GDM)

التفاصيل البيبلوغرافية
العنوان: 76-LB: Differences in Time-In-Range, Glycemic Variability, and the Glucose Management Indicator in Pregnant Women with Type 1 (T1D), Type 2 (T2D), and Gestational Diabetes (GDM)
المؤلفون: Selassie J. Ogyaadu, Xiaohe Zhang, Kristen Nelson, Grenye O’Malley, Camilla Levister, Saloni Shah, Carol J. Levy, Scott J. Brackett, Kristin Castorino, Sarit Polsky, Gal Haroush
المصدر: Diabetes. 69
بيانات النشر: American Diabetes Association, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Pregnancy, medicine.medical_specialty, Continuous glucose monitoring, Obstetrics, business.industry, Endocrinology, Diabetes and Metabolism, medicine.disease, Glucose management, Gestational diabetes, Hba1c level, Diabetes mellitus, Internal Medicine, medicine, business, Glycemic
الوصف: Glycemic control varies among different cohorts of pregnant women with diabetes. Most studies examining differences between groups using continuous glucose monitoring (CGM) data were performed with older CGM systems worn for 2-7 days. We examined differences in glycemic control and glycemic variability (GV) between pregnant women (n=32) with T1D (n=20), T2D (n=3), or GDM (n=9) in the 2nd and 3rd trimesters using the Dexcom G6 CGM system, worn for 10 days as part of a pregnancy CGM accuracy trial. Pair-wise comparisons were made between groups and group heterogeneity testing was performed. No adjustments were made for multiple comparisons analyses. Most women required insulin therapy (26/32, 81%). The baseline HbA1C levels were similar between groups (Table). The glucose management indicator (GMI) was numerically similar to HbA1C for the T1D and GDM cohorts. Time spent >140 mg/dL (p=0.009) was highest and time in range (63-140 mg/dL) was lowest (p=0.001) in women with T1D compared to the other groups. The coefficient of variation (CV) and mean amplitude of glycemic excursions (MAGE) were highest in the T1D group, lowest in the GDM group, and intermediate in the T2D group (p Disclosure S. Polsky: None. C.J. Levy: Consultant; Self; Dexcom, Inc. Employee; Spouse/Partner; Allergan plc. Research Support; Self; Abbott, Dexcom, Inc., Insulet Corporation. X. Zhang: Employee; Self; Dexcom, Inc. S. Shah: Employee; Self; Dexcom, Inc. G. Haroush: None. K. Nelson: None. G. O’Malley: Research Support; Self; Abbott, Dexcom, Inc. S.J. Ogyaadu: None. S.J. Brackett: None. C. Levister: None. K.N. Castorino: Research Support; Self; Abbott, Dexcom, Inc., Medtronic, Mylan, Novo Nordisk Inc. Funding Dexcom, Inc.
تدمد: 1939-327X
0012-1797
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1549d2e7512c2ce0cc3a6d2263ee9aecTest
https://doi.org/10.2337/db20-76-lbTest
حقوق: CLOSED
رقم الانضمام: edsair.doi...........1549d2e7512c2ce0cc3a6d2263ee9aec
قاعدة البيانات: OpenAIRE