Estrogen contributes to the sex difference in the occurrence of senescence-related T cells during the development of visceral adipose tissue inflammation
| العنوان: | Estrogen contributes to the sex difference in the occurrence of senescence-related T cells during the development of visceral adipose tissue inflammation |
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| المؤلفون: | Natsumi Imano, Kensaku Shojima, Kayoko Tamaki, Ken Shinmura |
| المصدر: | American Journal of Physiology-Heart and Circulatory Physiology. 324:H662-H674 |
| بيانات النشر: | American Physiological Society, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Physiology, Physiology (medical), Cardiology and Cardiovascular Medicine |
| الوصف: | The accumulation pattern of adipose tissue differs between the sexes; however, it is unclear whether sex differences exist during the development of adipose tissue inflammation and whether estrogen plays a role. We demonstrated sex differences in immune cells’ subpopulation of visceral adipose tissue. The proinflammatory environment appeared earlier in males than in females. In addition, our results suggest that estrogen plays a role in visceral adipose tissue inflammation, particularly by regulating the appearance of senescence-related T cells. |
| تدمد: | 1522-1539 0363-6135 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::0a08940e0a830c034a91229ccdc0ce68Test https://doi.org/10.1152/ajpheart.00469.2022Test |
| رقم الانضمام: | edsair.doi...........0a08940e0a830c034a91229ccdc0ce68 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15221539 03636135 |
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