Acylphloroglucinol Derivatives with a Tricyclo-[4.4.1.11,4] Dodecane Skeleton from Garcinia bracteata Fruits
| العنوان: | Acylphloroglucinol Derivatives with a Tricyclo-[4.4.1.11,4] Dodecane Skeleton from Garcinia bracteata Fruits |
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| المؤلفون: | Zhinan Mei, Jing Xu, Rui Qin, Yu Chen, Haida Teng, Hong Liu, Guangzhong Yang, Qing Xue |
| المصدر: | The Journal of Organic Chemistry. 85:6620-6625 |
| بيانات النشر: | American Chemical Society (ACS), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | chemistry.chemical_compound, Garcibracteatone, chemistry, 010405 organic chemistry, Dodecane, Stereochemistry, Organic Chemistry, 010402 general chemistry, Garcinia bracteata, 01 natural sciences, Skeleton (computer programming), 0104 chemical sciences, Nitric oxide |
| الوصف: | Two novel polycyclic polyprenylated acylphloroglucinols (PPAPs), garcibractinones A (1) and B (2), as well as three known analogues doitunggarcinones A-B (3-4) and garcibracteatone (5) were isolated from Garcinia bracteata fruits. Their structures were elucidated by comprehensive spectroscopic methods and single crystal X-ray diffraction. Compounds 1 and 2 possess an unprecedented caged tricyclo-[4.4.1.11,4] dodecane skeleton, and their biosynthetic pathways are also proposed. Compounds 1-2 were tested for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 macrophages. |
| تدمد: | 1520-6904 0022-3263 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::09a9ffa2909875b180408cdaf9f43a45Test https://doi.org/10.1021/acs.joc.0c00637Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........09a9ffa2909875b180408cdaf9f43a45 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15206904 00223263 |
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