Free thyroxine and triiodothyronine are associated with renal function in normoalbuminuric euthyroid type 1 diabetic patients

التفاصيل البيبلوغرافية
العنوان: Free thyroxine and triiodothyronine are associated with renal function in normoalbuminuric euthyroid type 1 diabetic patients
المؤلفون: Tomislav Bulum, Marijana Vučić Lovrenčić, Ingrid Prkačin, Lea Duvnjak
المساهمون: Laganović M, Bubić I
المصدر: Acta Clinica Croatica, Vol 60., Iss Supplement 1, Pp 39-45 (2021)
سنة النشر: 2020
مصطلحات موضوعية: endocrine system, Type 1 diabetes, endocrine system diseases, Thyroid hormones, Albuminuria, Medicine, thyroid hormones, type 1 diabetes, renal function, albuminuria, hormones, hormone substitutes, and hormone antagonists, Renal function, thyroid functin, renal function, type 1 diabetes
الوصف: Study included 272 normoalbuminuric T1DM with normal thyroid function and before any interventions with statins and antihypertensive medications including those that might affect renal function (ACE inhibitors or angiotensin II receptor blockers). Euthyroidism was defined as TSH, fT3 and fT4 within the normal reference range. Urinary albumin excretion rate (UAE) was measured from at least two 24-h urine samples. Study included patients with glomerular filtration rate (GFR) > 60 mlmin-11.73m-2, estimated with Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula. RESULT AND CONCLUSION The average age was approximately 34 years and 55% of subjects were male. Mean/median values of BMI (24 kg/m2), systolic and diastolic blood pressure (120/80 mmHg), HDL cholesterol (1.6 mmol/L), and triglycerides (0.9 mmol/L) were within the normal range for T1DM, with slightly elevated HbA1c (7.3%) and LDL cholesterol (2.7 mmol/L) levels. fT4 significantly correlated with serum creatinine, eGFR and UAE (r=-0.12, 0.34 and -0.13, respectively, for all p
اللغة: English
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f6f04b829be36f106a780b9211e66679Test
https://www.bib.irb.hr/1090241Test
حقوق: OPEN
رقم الانضمام: edsair.dedup.wf.001..f6f04b829be36f106a780b9211e66679
قاعدة البيانات: OpenAIRE