دورية
Mast cells in an angiosarcoma complicating Xeroderma pigmentosum in a 13-year-old girl
| العنوان: | Mast cells in an angiosarcoma complicating Xeroderma pigmentosum in a 13-year-old girl |
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| المؤلفون: | Ludolph-Hauser, Dagmar, Thoma-Greber, Eva, Sander, Christian, Sommerhoff, Christian P., Röcken, Martin |
| المصدر: | Journal of the American Academy of Dermatology; November 2000, Vol. 43 Issue: 5 p900-902, 3p |
| مستخلص: | A cutaneous angiosarcoma, a rare tumor that occurs almost exclusively in sunexposed skin of individuals older than 50 years, developed in an adolescent with Xeroderma pigmentosum (XP). As this is the second report of a child with angiosarcoma and XP, ultraviolet-induced DNA damage may be involved in the pathogenesis of this tumor. Strongly increased numbers of mast cells were found, particularly in the peripheral tumor area, which may reflect with the requirement of mast cells for the growth of vascular structures or a role for mast cells in the antitumor immune response. (J Am Acad Dermatol 2000;43:900-2.) |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 01909622 10976787 |
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| DOI: | 10.1067/mjd.2000.101883 |