دورية
Prognostic impact of cooccurring mutations in FLT3-ITD pediatric acute myeloid leukemia
العنوان: | Prognostic impact of cooccurring mutations in FLT3-ITD pediatric acute myeloid leukemia |
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المؤلفون: | Tarlock, Katherine, Gerbing, Robert B., Ries, Rhonda E., Smith, Jenny L., Leonti, Amanda, Huang, Benjamin J., Kirkey, Danielle, Robinson, Leila, Peplinksi, Jack H., Lange, Beverly, Cooper, Todd M., Gamis, Alan S., Kolb, E. Anders, Aplenc, Richard, Pollard, Jessica A., Alonzo, Todd A., Meshinchi, Soheil |
المصدر: | Blood Advances; May 2024, Vol. 8 Issue: 9 p2094-2103, 10p |
مستخلص: | •Cooccurring mutational profile and not allelic ratio determines clinical outcomes for patients with FLT3-ITD.•Therapy intensification improves survival for patients with FLT3-ITD; however, those with cooccurring poor-risk mutations still fare poorly. |
قاعدة البيانات: | Supplemental Index |
تدمد: | 24739529 24739537 |
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DOI: | 10.1182/bloodadvances.2023011980 |