دورية
Cleft Lip and/or Palate Repair in Children With Hypopituitarism: Analysis of the Kids’ Inpatient Database
| العنوان: | Cleft Lip and/or Palate Repair in Children With Hypopituitarism: Analysis of the Kids’ Inpatient Database |
|---|---|
| المؤلفون: | Poupore, Nicolas S., Chidarala, Shreya, Nguyen, Shaun A., Teufel, Ronald J., Patel, Krishna G., Pecha, Phayvanh P., Carroll, William W. |
| المصدر: | The Cleft Palate-Craniofacial Journal; January 2024, Vol. 61 Issue: 1 p94-102, 9p |
| مستخلص: | Objective Children with hypopituitarism (CwHP) can present with orofacial clefting, frequently in the setting of multiple midline anomalies. Hypopituitarism (HP) can complicate medical and surgical care; the perioperative risk in CwHP during the traditionally lower risk cleft lip and/or palate (CL/P) repair is not well described. The objective of this study is to examine the differences in complications and mortality of CL/P repair in CwHP compared to children without hypopituitarism (CwoHP).Design A retrospective cross-sectional analysis.Setting The 1997 to 2019 Kids’ Inpatient Databases (KID).Patients Children 3 years old and younger who underwent CL/P repair.Main Outcome Measure(s) Complications and mortality.Results A total of 34 106 weighted cases were analyzed, with 86 having HP. CwHP had a longer length of stay (3.0 days [IQR 2.0-10.0] vs 1.0 day [IQR 1.0-2.0], P< .001) and higher rates of complications and mortality (12.8% vs 2.9%, P< .001) compared to CwoHP. Controlling for demographic factors, CwHP had 6.61 higher odds of complications and mortality than CwoHP (95% CI 3.38-12.94, P< .001).Conclusions CwHP can present with a CL/P and other midline defects that can increase the complexity of their care. These data show a significant increase in length of stay, complications, and mortality in CwHP undergoing CL/P repair. Increased multidisciplinary attention and monitoring may be needed for these children peri- and postoperatively, especially if additional comorbidities are present. Further studies on perioperative management in this population are warranted to reduce morbidity and mortality. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 10556656 15451569 |
|---|---|
| DOI: | 10.1177/10556656221117435 |