CD38 antibody re-treatment in daratumumab-refractory multiple myeloma after time on other therapies

التفاصيل البيبلوغرافية
العنوان: CD38 antibody re-treatment in daratumumab-refractory multiple myeloma after time on other therapies
المؤلفون: Perez de Acha, Olivia, Reiman, Lauren, Jayabalan, David S., Walker, Zachary J., Bosma, Grace, Keller, Alana L., Parzych, Sarah E., Abbott, Diana, Idler, Beau M., Ribadeneyra, Drew, Niesvizky, Ruben, Forsberg, Peter A., Mark, Tomer M., Sherbenou, Daniel W.
المصدر: Blood Advances; November 2023, Vol. 7 Issue: 21 p6430-6440, 11p
مستخلص: •We show that patients gradually recover CD38 antibody sensitivity while on other treatments.•We conclude that re-treatment efficacy may improve by waiting 1 year before rechallenge and alternating anti-CD38 agents.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:24739529
24739537
DOI:10.1182/bloodadvances.2023010162