دورية
Spatial and molecular profiling of the mononuclear phagocyte network in classic Hodgkin lymphoma
العنوان: | Spatial and molecular profiling of the mononuclear phagocyte network in classic Hodgkin lymphoma |
---|---|
المؤلفون: | Stewart, Benjamin J., Fergie, Martin, Young, Matthew D., Jones, Claire, Sachdeva, Ashwin, Blain, Alex, Bacon, Chris M., Rand, Vikki, Ferdinand, John R., James, Kylie R., Mahbubani, Krishnaa T., Hook, Liz, Jonas, Nicolaas, Coleman, Nicholas, Saeb-Parsy, Kourosh, Collin, Matthew, Clatworthy, Menna R., Behjati, Sam, Carey, Christopher D. |
المصدر: | Blood; May 2023, Vol. 141 Issue: 19 p2343-2358, 16p |
مستخلص: | •Tumor-associated MNP are diverse and spatially polarized: cDC2 colocalize with malignant HRSCs; plasmacytoid and activated DCs are excluded.•DCs, monocytes, and macrophages exist in an inflammatory niche in close proximity to HRSCs, and all express inhibitory molecules. |
قاعدة البيانات: | Supplemental Index |
تدمد: | 00064971 15280020 |
---|---|
DOI: | 10.1182/blood.2022015575 |