Vertebral to Basilar Thrombus Migration Post Intravenous Thrombolysis

التفاصيل البيبلوغرافية
العنوان: Vertebral to Basilar Thrombus Migration Post Intravenous Thrombolysis
المؤلفون: Banerjee, Ankur, Marzoughi, Sina, Ohara, Tomoyuki, Horn, MacKenzie, Zerna, Charlotte, Menon, Bijoy K., Demchuk, Andrew M.
المصدر: The Canadian Journal of Neurological Sciences; January 2023, Vol. 50 Issue: 1 p119-122, 4p
مستخلص: ABSTRACT:Recombinant tissue plasminogen activator improves outcomes in acute ischemic stroke. Alteplase may result in thrombus migration (TM) distally to a critical arterial supply that can worsen perfusion to eloquent brain tissue. Alteplase-related stroke recanalization and clot migration in vertebral artery (VA) occlusion whereby the clot migrates to the basilar artery (BA) may be harmful. We identified seven subjects with isolated symptomatic vertebral occlusion. Two cases suffered early neurologic deterioration due to TM from VA to BA following alteplase. Precautionary transfer to thrombectomy centers may be warranted in alteplase-treated symptomatic VA occlusions in case of migration to basilar occlusion.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:03171671
DOI:10.1017/cjn.2021.237