دورية
Factor VII in Subjects at Risk for Thromboembolism: Activation or Increased Synthesis?
| العنوان: | Factor VII in Subjects at Risk for Thromboembolism: Activation or Increased Synthesis? |
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| المؤلفون: | Orlando, M., Leri, O., Macioce, G., Mattia, G., Ferri, G.M. |
| المصدر: | Haemostasis; January 1987, Vol. 17 Issue: 6 p340-343, 4p |
| مستخلص: | In this study the preliminary results obtained by investigating factor VII:antigen and activity in 38 subjects with arterial disease of the extremities are reported. The antigen determination (VIl:Ag) was performed by using an inhibitor neutralization assay; factor VII activity (VIl:C) was determined by one-stage assay with human factor VII artificially depleted plasma. All the patients showed increased levels of VIl:C and VIl·Ag compared to the reference population (p < 0.001). There is a significant correlation between VIl:C and VIl:Ag (r = 0.47), but the ratio VIl:C/VIl:Ag is slightly increased. Our results confirm that elevated levels of factor VII are present in patients with tendency to thrombosis. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 03010147 14230038 |
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| DOI: | 10.1159/000215767 |