دورية
Low Absolute Lymphocyte Count (ALC) at Diagnosis Is An IPSS-Independent Predictor of Poorer Survival in Myelodysplastic Syndromes (MDS)
| العنوان: | Low Absolute Lymphocyte Count (ALC) at Diagnosis Is An IPSS-Independent Predictor of Poorer Survival in Myelodysplastic Syndromes (MDS) |
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| المؤلفون: | Jacobs, Nisha L, Holtan, Shernan G, Porrata, Luis F, Markovic, Svetomir N, Tefferi, Ayalew, Steensma, David P. |
| المصدر: | Blood; November 2008, Vol. 112 Issue: 11 p3633-3633, 1p |
| مستخلص: | Background:The prognostic significance of lymphocyte counts and immune status has been carefully examined in lymphoid malignancies, but the importance of the lymphocyte count in chronic myeloid neoplasms is less clear. In a recent analysis of MDS cases associated with deletion of chromosome 5q (Holtan SG et al AmJHem2008 Epub 12Jun), we observed that an ALC >1.2 × 109cells/L at diagnosis is independently associated with improved survival. The prognostic value of ALC in MDS not associated with del(5q) is unknown. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 00064971 15280020 |
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| DOI: | 10.1182/blood.V112.11.3633.3633 |