Single Doses of Antibody Drug Conjugates (ADCs) Targeted to CD117 or CD45 Have Potent In Vivo Anti-Leukemia Activity and Survival Benefit in Patient Derived AML Models

التفاصيل البيبلوغرافية
العنوان: Single Doses of Antibody Drug Conjugates (ADCs) Targeted to CD117 or CD45 Have Potent In Vivo Anti-Leukemia Activity and Survival Benefit in Patient Derived AML Models
المؤلفون: Proctor, Jennifer L, Hyzy, Sharon L., Adams, Hillary L, Brooks, Melissa L., Gabros, Andrew D, McDonough, Sean M, Kien, Lena, Aslanian, Sharon, Pearse, Bradley R, Palchaudhuri, Rahul, Li, Qing, Kallen, Nathan M, Sarma, Ganapathy, McShea, Molly A, Ladwig, Danielle, Dushime, Junia, Panwar, Rajiv, McDonagh, Charlotte F, Boitano, Anthony E., Cooke, Michael P.
المصدر: Blood; November 2018, Vol. 132 Issue: Supplement 1 p3316-3316, 1p
مستخلص: Proctor: Magenta Therapeutics: Employment, Equity Ownership. Hyzy:Magenta Therapeutics: Employment, Equity Ownership. Adams:Magenta Therapeutics: Employment, Equity Ownership. Brooks:Magenta Therapeutics: Employment, Equity Ownership. Gabros:Magenta Therapeutics: Employment, Equity Ownership. McDonough:Magenta Therapeutics: Employment, Equity Ownership. Kien:Magenta Therapeutics: Employment, Equity Ownership. Aslanian:Magenta Therapeutics: Employment, Equity Ownership. Pearse:Magenta Therapeutics: Employment, Equity Ownership, Patents & Royalties. Palchaudhuri:Magenta Therapeutics: Employment, Equity Ownership, Patents & Royalties; Harvard University: Patents & Royalties. Li:Magenta Therapeutics: Employment, Equity Ownership. Kallen:Magenta Therapeutics: Employment, Equity Ownership. Sarma:Magenta Therapeutics: Employment, Equity Ownership. McShea:Magenta Therapeutics: Employment, Equity Ownership. Ladwig:Magenta Therapeutics: Employment, Equity Ownership. Dushime:Magenta Therapeutics: Employment, Equity Ownership. Panwar:Magenta Therapeutics: Employment, Equity Ownership, Patents & Royalties. McDonagh:Magenta Therapeutics: Employment, Equity Ownership, Patents & Royalties. Boitano:Magenta Therapeutics: Employment, Equity Ownership, Patents & Royalties. Cooke:Magenta Therapeutics: Employment, Equity Ownership, Patents & Royalties.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00064971
15280020
DOI:10.1182/blood-2018-99-112726