دورية
Cytotoxic Effector Function of CD4-Independent, CD8T Cells Is Mediated by TNF-TNFR
| العنوان: | Cytotoxic Effector Function of CD4-Independent, CD8T Cells Is Mediated by TNF-TNFR |
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| المؤلفون: | Zimmerer, Jason M., Horne, Phillip H., Fiessinger, Lori A., Fisher, Mason G., Pham, Thomas A., Saklayen, Samiya L., Bumgardner, Ginny L. |
| المصدر: | Transplantation; December 2012, Vol. 94 Issue: 11 p1103-1110, 8p |
| مستخلص: | Liver parenchymal cell allografts initiate both CD4-dependent and CD4-independent, CD8T cell–mediated acute rejection pathways. The magnitude of allospecific CD8T cell in vivo cytotoxic effector function is maximal when primed in the presence of CD4T cells. The current studies were conducted to determine if and how CD4T cells might influence cytotoxic effector mechanisms. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 00411337 15346080 |
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| DOI: | 10.1097/TP.0b013e318270f3c0 |