التفاصيل البيبلوغرافية
العنوان: |
ECE1gene variant shows tendency toward chronic kidney disease advancement among autosomal polycystic kidney disease patients |
المؤلفون: |
Annapareddy, Shiva Nagendra Reddy, Kumbakonam, Vinuutna Sravani, Elumalai, Ramprasad, Ramanathan, Gnanasambandan, Periyasamy, Soundararajan, Lakkakula, Bhaskar V.K.S. |
المصدر: |
Hong Kong Journal of Nephrology; April 2016, Vol. 18 Issue: 1 p20-25, 6p |
مستخلص: |
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by numerous epithelium-lined cysts in the kidney and is the leading genetic cause of end-stage renal disease worldwide. Endothelin-1 is a potent vasoactive peptide implicated in the regulation of basal vascular tone. Endothelin (ET)-converting enzyme 1 (ECE1) is well known for its critical role in the process of ET. |
قاعدة البيانات: |
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