التفاصيل البيبلوغرافية
| العنوان: |
Recombinant baculoviruses as vehicles for presentation and adjuvancy of antigens for the development of new tuberculosis candidate vaccines |
| المؤلفون: |
Molinari, Paula, Bianco, Verónica, Peralta, Andrea, Gravisaco, María José, Morón, Gabriel, Bigi, Fabiana, Taboga, Oscar |
| المصدر: |
Procedia in Vaccinology; January 2009, Vol. 1 Issue: 1 p81-84, 4p |
| مستخلص: |
Recent studies have shown adjuvant properties of baculovirus by enhancing and modulating the immune response in mammals. This ability has been explained in part by the activation of the innate immunity. In addition, baculovirus induce a vigorous cytotoxic response characterized by a large number of IFNγ-producing cells. By flow cytometry analysis, we demonstrated that, when inoculated in mice, wild type baculovirus induce IFNγ and IL-12 expression and activation of NK and NKT cells. |
| قاعدة البيانات: |
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