دورية
The Role of Dipeptidyl Peptidase IV (DP IV) Enzymatic Activity in T Cell Activation and Autoimmunity
| العنوان: | The Role of Dipeptidyl Peptidase IV (DP IV) Enzymatic Activity in T Cell Activation and Autoimmunity |
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| المؤلفون: | Reinhold, D., Kähne, T., Steinbrecher, A., Wrenger, S., Neubert, K., Ansorge, S., Brocke, S. |
| المصدر: | Biological Chemistry; August 2002, Vol. 383 Issue: 7-8 p1133-1138, 6p |
| مستخلص: | AbstractActivated T lymphocytes express high levels of dipeptidyl peptidase IV (DP IV)/CD26. Recent studies support the notion that DP IV may play an important role in the regulation of differentiation and growth of T lymphocytes. This article gives a short overview on DP IV/CD26 expression and effects on immune cells in vitro and in vivo. A major focus of this review are clinical aspects of the function of CD26 on hematopoietic cells and the potential usage of synthetic DP IV inhibitors as therapeutics in inflammatory disorders. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 14316730 14374315 |
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| DOI: | 10.1515/BC.2002.123 |