دورية أكاديمية

Use of Lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association.

التفاصيل البيبلوغرافية
العنوان: Use of Lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association.
المؤلفون: Wilson, Don P., Jacobson, Terry A., Jones, Peter H., Koschinsky, Marlys L., McNeal, Catherine J., Nordestgaard, Børge G., Orringer, Carl E.
المصدر: Journal of Clinical Lipidology; Sep2022, Vol. 16 Issue 5, pe77-e95, 19p
مصطلحات موضوعية: LIPOPROTEINS, BIOMARKERS, GENETICS, STROKE, BLOOD plasma, CARDIOVASCULAR diseases, MYOCARDIAL infarction
مستخلص: Lipoprotein(a) [Lp(a)] is a well-recognized, independent risk factor for atherosclerotic cardiovascular disease, with elevated levels estimated to be prevalent in 20% of the population. Observational and genetic evidence strongly support a causal relationship between high plasma concentrations of Lp(a) and increased risk of atherosclerotic cardiovascular disease–related events, such as myocardial infarction and stroke, and valvular aortic stenosis. In this scientific statement, we review an array of evidence-based considerations for testing of Lp(a) in clinical practice and the utilization of Lp(a) levels to inform treatment strategies in primary and secondary prevention. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Supplemental Index
الوصف
تدمد:19332874
DOI:10.1016/j.jacl.2022.08.007