دورية أكاديمية

Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents.

التفاصيل البيبلوغرافية
العنوان: Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents.
المؤلفون: Norbom, Linn B., Hanson, Jamie, van der Meer, Dennis, Ferschmann, Lia, Røysamb, Espen, von Soest, Tilmann, Andreassen, Ole A., Agartz, Ingrid, Westlye, Lars T., Tamnes, Christian K.
المصدر: Developmental Cognitive Neuroscience; Aug2022, Vol. 56, pN.PAG-N.PAG, 1p
مستخلص: Gradients in parental socioeconomic status (SES) are closely linked to important life outcomes in children and adolescents, such as cognitive abilities, school achievement, and mental health. Parental SES may also influence brain development, with several magnetic resonance imaging (MRI) studies reporting associations with youth brain morphometry. However, MRI signal intensity metrics have not been assessed, but could offer a microstructural correlate, thereby increasing our understanding of SES influences on neurobiology. We computed a parental SES score from family income, parental education and parental occupation, and assessed relations with cortical microstructure as measured by T1w/T2w ratio (n = 504, age = 3–21 years). We found negative age-stabile relations between parental SES and T1w/T2w ratio, indicating that youths from lower SES families have higher ratio in widespread frontal, temporal, medial parietal and occipital regions, possibly indicating a more developed cortex. Effect sizes were small, but larger than for conventional morphometric properties i.e. cortical surface area and thickness, which were not significantly associated with parental SES. Youths from lower SES families had poorer language related abilities, but microstructural differences did not mediate these relations. T1w/T2w ratio appears to be a sensitive imaging marker for further exploring the association between parental SES and child brain development. • Composite and sub-factor scores of parental socioeconomic status. • Youth cortical microstructure measured by T1w/T2w ratio (n = 504, age = 3–21 years). • Widespread negative relations with socioeconomic status and regional T1w/T2w ratio. • Youths from families with lower socioeconomic status had poorer language abilities. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Supplemental Index
الوصف
تدمد:18789293
DOI:10.1016/j.dcn.2022.101132