دورية أكاديمية

Methionine hydroxy analogue prevents oxidative damage and improves antioxidant status of intestine and hepatopancreas for juvenile Jian carp ( Cyprinus carpio var. Jian).

التفاصيل البيبلوغرافية
العنوان: Methionine hydroxy analogue prevents oxidative damage and improves antioxidant status of intestine and hepatopancreas for juvenile Jian carp ( Cyprinus carpio var. Jian).
المؤلفون: FENG, L., XIAO, W.-W., LIU, Y., JIANG, J., HU, K., JIANG, W.-D., LI, S.-H., ZHOU, X.-Q.
المصدر: Aquaculture Nutrition; Dec2011, Vol. 17 Issue 6, p595-604, 10p
مصطلحات موضوعية: METHIONINE, NATURAL immunity, ANIMAL nutrition, ANTIOXIDANTS, OXIDATIVE stress, CARP, FISH anatomy
مستخلص: Oxidative damage and antioxidant status of intestine and hepatopancreas for juvenile Jian carp ( Cyprinus carpio var. Jian) fed graded levels of methionine hydroxy analogue (MHA: 0, 5.1, 7.6, 10.2, 12.7, 15.3 g kg−1 diet) for 60 days were studied. Radical scavenging ability, antioxidant enzymes activities such as superoxide dismutase (SOD), catalase (CAT), glutathione- S-transferase (GST), glutathione peroxidase (GPX) and glutathione reducase (GR), as well as glutathione (GSH), protein carbonyl (PC) and malondialdehyde (MDA) contents were assayed in these tissues. Results indicated that anti-superoxide anion capacity in intestine and anti-hydroxyl radical capacity in hepatopancreas significantly improved with dietary MHA levels up to 7.6 and 10.2 g kg−1 diet respectively, whereupon they decreased ( P < 0.05). SOD, CAT, GST, GPX, GR activities in intestine and hepatopancreas, as well as GSH content in hepatopancreas significantly increased with optimal MHA levels which were in the range of 5.1-10.2 g kg−1 diet, and thereafter decreased ( P < 0.05). Meanwhile, MDA and PC contents in these tissues together with GOT and GPT activities in plasma significantly decreased with optimal MHA levels which were in the range of 5.1-7.6 g kg−1 diet, and thereafter increased ( P < 0.05). These results suggested that MHA improved antioxidant status and depressed lipid and protein oxidation in intestine and hepatopancreas. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:13535773
DOI:10.1111/j.1365-2095.2011.00853.x