التفاصيل البيبلوغرافية
| العنوان: |
Effects of allicin supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity. |
| المؤلفون: |
Quan-Sheng Su, Ye Tian, Jian-Guo Zhang, Hui Zhang, Su, Quan-Sheng, Tian, Ye, Zhang, Jian-Guo, Zhang, Hui |
| المصدر: |
European Journal of Applied Physiology; Jun2008, Vol. 103 Issue 3, p275-283, 9p, 1 Chart, 4 Graphs |
| مصطلحات موضوعية: |
EXERCISE, ANTIOXIDANTS, ATHLETES, CREATINE kinase, MUSCLE strength, PHYSIOLOGY, PREVENTIVE medicine, ANTI-inflammatory agents, PHARMACEUTICAL encapsulation, COMPARATIVE studies, DIETARY supplements, DRUG administration, INTERLEUKINS, LACTATE dehydrogenase, RESEARCH methodology, MEDICAL cooperation, ORAL drug administration, PAIN, RESEARCH, RUNNING, SUPEROXIDE dismutase, TIME, EVALUATION research, PAIN measurement, RANDOMIZED controlled trials, SULFUR acids, BLIND experiment, SKELETAL muscle |
| مستخلص: |
To investigate the effects of allicin supplementation on exercise-induced muscle damage (EIMD), interleukin-6 (IL-6), and antioxidative capacity, a double-blinded, placebo-controlled study was conducted in well-trained athletes. Subjects were randomly assigned to an allicin supplementation group (AS group) and a control group, and received either allicin or placebo for 14 days before and 2 days after a downhill treadmill run. Plasma creatine kinase (CK), muscle-specific creatine kinase (CK-MM), lactate dehydrogenase (LDH), IL-6, superoxide dismutase (SOD), total antioxidative capacity (TAC), and perceived muscle soreness were measured pre and post exercise. AS group had significantly lower plasma levels of CK, CK-MM and IL-6, and reduced perceived muscle soreness after exercise, when compared with the control group. AS group also demonstrated a trend toward reducing plasma concentration of LDH after exercise (P = 0.08), although not statistically significant. Allicin supplementation induced a higher value of TAC at rest, and this higher value was maintained 48 h after exercise, however, there was no difference in SOD values after exercise between the two groups. The results suggested that allicin might be a potential agent to reduce EIMD. Further studies concerning anti-inflammatory and anti-oxidative effects of allicin on EIMD are needed. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
