دورية أكاديمية

Controlled oxygen delivery to power tissue regeneration.

التفاصيل البيبلوغرافية
العنوان: Controlled oxygen delivery to power tissue regeneration.
المؤلفون: Zoneff, Elizabeth, Wang, Yi, Jackson, Colin, Smith, Oliver, Duchi, Serena, Onofrillo, Carmine, Farrugia, Brooke, Moulton, Simon E., Williams, Richard, Parish, Clare, Nisbet, David R., Caballero-Aguilar, Lilith M.
المصدر: Nature Communications; 5/22/2024, Vol. 15 Issue 1, p1-16, 16p
مصطلحات موضوعية: REGENERATION (Biology), OXYGEN, BIOMATERIALS, EMBRYOLOGY, HOMEOSTASIS, TISSUES
مستخلص: Oxygen plays a crucial role in human embryogenesis, homeostasis, and tissue regeneration. Emerging engineered regenerative solutions call for novel oxygen delivery systems. To become a reality, these systems must consider physiological processes, oxygen release mechanisms and the target application. In this review, we explore the biological relevance of oxygen at both a cellular and tissue level, and the importance of its controlled delivery via engineered biomaterials and devices. Recent advances and upcoming trends in the field are also discussed with a focus on tissue-engineered constructs that could meet metabolic demands to facilitate regeneration. This review explores the role of oxygen and its delivery via engineered biomaterials in a plethora of physiological processes. This piece emphasises on the application of advanced oxygen delivery strategies, as well as discussing advances in oxygen-generating materials and oxygen-perfusing devices. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:20411723
DOI:10.1038/s41467-024-48719-x