التفاصيل البيبلوغرافية
| العنوان: |
Triple-Negative Breast Cancer Treatment Advancements: A Review of Evolving Strategies. |
| المؤلفون: |
Liu, Guozheng, Zhang, Yanwen, Huang, Yong |
| المصدر: |
European Journal of Cancer Care; 4/8/2024, Vol. 2024, p1-12, 12p |
| مصطلحات موضوعية: |
BREAST cancer prognosis, THERAPEUTIC use of antineoplastic agents, BREAST tumor treatment, THERAPEUTIC use of monoclonal antibodies, ANTIANDROGENS, MITOGEN-activated protein kinases, CANCER relapse, T cells, TRASTUZUMAB, BREAST tumors, IMMUNOTHERAPY, PROGRAMMED death-ligand 1, APOPTOSIS, ENZYME inhibitors, AGE distribution, TUMOR markers, METASTASIS, ADJUVANT chemotherapy, IMMUNE checkpoint inhibitors, COMBINED modality therapy, PROGRAMMED cell death 1 receptors, MTOR inhibitors, PROGRESSION-free survival, INDIVIDUALIZED medicine, PHENOTYPES, OVERALL survival |
| مستخلص: |
Women around the world are most frequently afflicted with breast cancer, and it is one of the most frequent causes of cancer death in females. Breast cancer is usually classified according to biomarker status, triple‐negative breast cancer (TNBC) represents a distinct subtype characterized by immunohistochemical findings that denote negativity for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (Her-2) on cancer tissue. It is more common in younger women than in other subtypes. As an invasive breast cancer subtype with a unique drug-resistant phenotype and metastatic burden, it has limited treatment options, and patients have a poor prognosis with high rates of local, distant recurrence and mortality, and there is still a lack of standardized treatment protocols for TNBC. In this review, we delve into the current treatment strategies for TNBC and explore the potential for new approaches and targets in the future. This trial is registered with NCT03997123. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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