التفاصيل البيبلوغرافية
| العنوان: |
Two new triterpenoid glycosides from Bacopa monnieri and their cytotoxic activity. |
| المؤلفون: |
Yen, Duong Thi Hai, Cuc, Nguyen Thi, Tai, Bui Huu, Van Kiem, Phan, Hoang Duc, Manh, Nhiem, Nguyen Xuan, Cho, Su-Hyeon, Jeong, Sung Baek, Seo, Yohan, Park, SeonJu |
| المصدر: |
Natural Product Research; Apr2024, Vol. 38 Issue 7, p1120-1126, 7p |
| مصطلحات موضوعية: |
TRITERPENOID saponins, BACOPA monnieri, COLON cancer, CANCER cells, LUNG cancer |
| مستخلص: |
Using combined chromatographic methods, two new triterpenoid glycosides, bacopasaponin K (1) and bacopasaponin L (2), along with eight known compounds, bacopaside IV (3), bacopaside VII (4), bacopasaponin E (5), bacoside A3 (6), bacopasaponin F (7), bacopasaponin C (8), bacopaside I (9), and bacopaside II (10) were isolated from the methanol extract of the Bacopa monnieri. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis, HR-ESI-MS and comparing with the NMR data reported in the literature. All these compounds were evaluated for their cytotoxic activity using the cell counting kit-8 (CCK-8) assay. Compounds 4, 6, 8, and 10 exhibited potential cytotoxic effects against human lung cancer cells (PC9) and human colon cancer cells (SW620). [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
