دورية أكاديمية

Colchicine to prevent sympathetic denervation after acute myocardial infarction: the COLD-MI trial.

التفاصيل البيبلوغرافية
العنوان: Colchicine to prevent sympathetic denervation after acute myocardial infarction: the COLD-MI trial.
المؤلفون: Huet, Fabien, Mariano-Goulart, Denis, Aguilhon, Sylvain, Delbaere, Quentin, Lacampagne, Alain, Fauconnier, Jérémy, Leclercq, Florence, Macia, Jean-Christophe, Akodad, Mariama, Jammoul, Nidal, Prunier, Fabrice, Mewton, Nathan, Angoulvant, Denis, Lozza, Catherine, Soltani, Sonia, Rodier, Annabelle, Grandemange, Sylvie, Dupuy, Anne-Marie, Cristol, Jean-Paul, Amico, Mailis
المصدر: European Heart Journal; 3/1/2024, Vol. 45 Issue 9, p725-727, 3p
مصطلحات موضوعية: MYOCARDIAL infarction, COLCHICINE, DENERVATION, SINGLE-photon emission computed tomography, MYOCARDIUM, ST elevation myocardial infarction
مستخلص: The article discusses the results of the COLD-MI trial, which aimed to explore the impact of colchicine on myocardial denervation in patients who had experienced an acute myocardial infarction (AMI). The study found that colchicine reduced myocardial denervation in both the infarcted and non-infarcted zones of the heart. However, there were no significant effects on other parameters such as necrosis size or left ventricular ejection fraction. The study also noted an increase in gastrointestinal side effects with colchicine use. Overall, the findings suggest that colchicine may have a positive effect on reducing cardiac denervation in patients after AMI. [Extracted from the article]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:0195668X
DOI:10.1093/eurheartj/ehae042