التفاصيل البيبلوغرافية
| العنوان: |
Predictive Factors of Cardiac Mortality Following TEER in Patients with Secondary Mitral Regurgitation. |
| المؤلفون: |
Imamura, Teruhiko, Tanaka, Shuhei, Ushijima, Ryuichi, Fukuda, Nobuyuki, Ueno, Hiroshi, Kinugawa, Koichiro, Kubo, Shunsuke, Yamamoto, Masanori, Saji, Mike, Asami, Masahiko, Enta, Yusuke, Nakashima, Masaki, Shirai, Shinichi, Izumo, Masaki, Mizuno, Shingo, Watanabe, Yusuke, Amaki, Makoto, Kodama, Kazuhisa, Yamaguchi, Junichi, Nakajima, Yoshifumi |
| المصدر: |
Journal of Clinical Medicine; Feb2024, Vol. 13 Issue 3, p851, 12p |
| مصطلحات موضوعية: |
MITRAL valve insufficiency, MITRAL valve, HEART failure, PEPTIDES, MORTALITY |
| مستخلص: |
Background: Transcatheter edge-to-edge mitral valve repair (TEER) has emerged as a viable approach to addressing substantial secondary mitral regurgitation. In the contemporary landscape where ultimate heart failure-specific therapies, such as cardiac replacement modalities, are available, prognosticating a high-risk cohort susceptible to early cardiac mortality post-TEER is pivotal for formulating an effective therapeutic regimen. Methods: Our study encompassed individuals with secondary mitral regurgitation and chronic heart failure enlisted in the multi-center (Optimized CathEter vAlvular iNtervention (OCEAN)-Mitral registry. We conducted an assessment of baseline variables associated with cardiac death within one year following TEER. Results: Amongst the 1517 patients (median age: 78 years, 899 males), 101 experienced cardiac mortality during the 1-year observation period after undergoing TEER. Notably, a history of heart failure-related admissions within the preceding year, utilization of intravenous inotropes, and elevated plasma B-type natriuretic peptide levels emerged as independent prognosticators for the primary outcome (p < 0.05 for all). Subsequently, we devised a novel risk-scoring system encompassing these variables, which significantly stratified the cumulative incidence of the 1-year primary outcome (16%, 8%, and 4%, p < 0.001). Conclusions: Our study culminated in the development of a new risk-scoring system aimed at predicting 1-year cardiac mortality post-TEER. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Clinical Medicine is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder