التفاصيل البيبلوغرافية
| العنوان: |
High Mitochondrial Haplotype Diversity Found in Three Pre-Hispanic Groups from Colombia. |
| المؤلفون: |
Uricoechea Patiño, Daniel, Collins, Andrew, García, Oscar Julián Romero, Santos Vecino, Gustavo, Cuenca, José Vicente Rodríguez, Bernal, Jaime E., Benavides Benítez, Escilda, Vergara Muñoz, Saray, Briceño Balcázar, Ignacio |
| المصدر: |
Genes; Oct2023, Vol. 14 Issue 10, p1853, 13p |
| مصطلحات موضوعية: |
MITOCHONDRIAL DNA, HAPLOTYPES, DNA analysis, NUCLEAR DNA, MITOCHONDRIA, HYPERVARIABLE regions |
| مصطلحات جغرافية: |
COLOMBIA |
| مستخلص: |
The analysis of mitochondrial DNA (mtDNA) hypervariable region (HVR) sequence data from ancient human remains provides valuable insights into the genetic structure and population dynamics of ancient populations. mtDNA is particularly useful in studying ancient populations, because it is maternally inherited and has a higher mutation rate compared to nuclear DNA. To determine the genetic structure of three Colombian pre-Hispanic populations and compare them with current populations, we determined the haplotypes from human bone remains by sequencing several mitochondrial DNA segments. A wide variety of mitochondrial polymorphisms were obtained from 33 samples. Our results support a high population heterogeneity among pre-Hispanic populations in Colombia. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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