التفاصيل البيبلوغرافية
| العنوان: |
Biokinetic model analysis with DTPA administration for a case of accidental inhalation of actinides in Japan. |
| المؤلفون: |
Tani, Kotaro, Ishigure, Nobuhito, Kim, Eunjoo, Tominaga, Takako, Tatsuzaki, Hideo, Akashi, Makoto, Kurihara, Osamu |
| المصدر: |
Radiation Protection Dosimetry; Oct2023, Vol. 199 Issue 15, p2025-2029, 5p |
| مصطلحات موضوعية: |
ACTINIDE elements, PLUTONIUM isotopes, RADIATION dosimetry, NUMERICAL analysis, BIOLOGICAL assay, PLUTONIUM |
| مصطلحات جغرافية: |
JAPAN |
| مستخلص: |
Accidental inhalation intake of plutonium isotopes and 241Am occurred at a Pu research facility in Japan in 2017, and the five workers involved in this accident were treated by the administration of Ca/Zn-diethylenetriaminepentaacetic acid (DTPA). For the worker who was most internally exposed, the therapy was continued over 1 y after the accident. Urinary samples collected before and after each administration were subject to bioassay to evaluate the efficacy of the dose reduction. This study performed numerical analyses using a biokinetic model dealing with 241Am-DTPA with reference to the European Coordinated Network on Radiation Dosimetry approach, which assumes that the complex of actinides and Ca/Zn-DTPA is generated in the designated compartments in the biokinetic model. The results of the model prediction well captured the trend of the observed urinary excretion in the long-term bioassay and would be useful to evaluate the efficacy of the Ca/Zn-DTPA administration for the worker involved in the accident. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
