دورية أكاديمية

Central venous-arterial carbon dioxide difference as an indicator of cardiac index.

التفاصيل البيبلوغرافية
العنوان: Central venous-arterial carbon dioxide difference as an indicator of cardiac index.
المؤلفون: Cuschieri, Joseph, Rivers, Emanuel P., Donnino, Michael W., Katilius, Marius, Jacobsen, Gordon, Nguyen, H. Bryant, Pamukov, Nikolai, Horst, H. Mathilda
المصدر: Intensive Care Medicine; Jun2005, Vol. 31 Issue 6, p818-822, 5p
مصطلحات موضوعية: CARBON dioxide, INTENSIVE care units, HOSPITALS, BLOOD gases, PULMONARY artery, PATIENTS, BLOOD gases analysis, CARDIAC output, COMPARATIVE studies, HEMODYNAMICS, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, REGRESSION analysis, RESEARCH, EVALUATION research, CENTRAL venous catheterization, SWAN-Ganz catheterization, PARTIAL pressure
مستخلص: Objective: The mixed venous-arterial (v-a) pCO(2) difference has been shown to be inversely correlated with the cardiac index (CI). A central venous pCO(2), which is easier to obtain, may provide similar information. The purpose of this study was to examine the correlation between the central venous-arterial pCO(2) difference and CI.Design: Prospective, cohort study.Setting: Intensive care unit of an urban tertiary care hospital.Patients and Participants: Eighty-three consecutive intensive care unit patients.Measurements: Simultaneous blood gases from the arterial, pulmonary artery (PA), and central venous (CV) catheters were obtained. At the same time point, cardiac indices were measured by the thermodilution technique (an average of three measurements). The cardiac indices obtained by the venous-arterial differences were compared with those determined by thermodilution.Results: The correlation (R(2)) between the mixed venous-arterial pCO(2) difference and cardiac index was 0.903 (p <0.0001), and the correlation between the central venous-arterial pCO(2) difference and cardiac index was 0.892 (p <0.0001). The regression equations for these relationships were natural log (CI)=1.837-0.159 (v-a) CO(2) for the PA and natural log (CI)=1.787-0.151 (v-a) CO(2) for the CV (p <0.0001 for both). The root-mean-squared error for the PA and CV regression equations were 0.095 and 0.101, respectively.Conclusion: Venous-arterial pCO(2) differences obtained from both the PA and CV circulations inversely correlate with the cardiac index. Substitution of a central for a mixed venous-arterial pCO(2) difference provides an accurate alternative method for calculation of cardiac output. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:03424642
DOI:10.1007/s00134-005-2602-8