التفاصيل البيبلوغرافية
| العنوان: |
A Trial to Evaluate Target Occupancy of Scopolamine at the Muscarinic M1 Receptor. |
| المصدر: |
Hepatitis Weekly; 9/15/2023, p46-46, 1p |
| مصطلحات موضوعية: |
MUSCARINIC receptors, SCOPOLAMINE, BRAIN imaging, PARASYMPATHOMIMETIC agents, POSITRON emission tomography |
| مستخلص: |
The data from those 2 subjects will be reviewed to determine the timepoint for tracer injection for the post scopolamine [11C] EMO PET scan in the next 2 subjects (e.g., tracer injection at 24-hour or 1-hour post-dose). Treatment with another investigational drug or other intervention within 30 days of the screening visit, or participation in another trial involving radiotracer administration within 1 week of dosing day. Keywords: Anticholinergic Antiemetics; Anticholinergics; Antiemetic-Antivertigo Agents; Antispasmodics; Azabicyclo Compounds; Central Nervous System Agents; Cholinergic Receptors; Clinical Research; Clinical Trials and Studies; Drugs and Therapies; Drugs and Therapies - Antiemetic-Antivertigo Agents; G-Protein-Coupled Receptors; Health and Medicine; Membrane Proteins; Muscarinic Receptors; Mydriatics; Ophthalmic Preparations; Pharmaceuticals; Scopolamine; Scopolamine Therapy; Tropanes EN Anticholinergic Antiemetics Anticholinergics Antiemetic-Antivertigo Agents Antispasmodics Azabicyclo Compounds Central Nervous System Agents Cholinergic Receptors Clinical Research Clinical Trials and Studies Drugs and Therapies Drugs and Therapies - Antiemetic-Antivertigo Agents G-Protein-Coupled Receptors Health and Medicine Membrane Proteins Muscarinic Receptors Mydriatics Ophthalmic Preparations Pharmaceuticals Scopolamine Scopolamine Therapy Tropanes 46 46 1 09/11/23 20230915 NES 230915 2023 SEP 14 (NewsRx) -- By a News Reporter-Staff News Editor at Hepatitis Weekly -- Staff editors report on the newly launched clinical trial, NCT06014385, which has the following summary description: "The purpose of this study is to assess the target occupancy (TO) of scopolamine at M1 Muscarinic Receptors in the brain after single I.V. doses of scopolamine, in healthy control subjects, using the radiotracer [11C]EMO (also known as [11C]LSN3172176).". [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
